Research Topic/Project

M3-project 2: Orchestration of phagocytic macrophage activity to clear bacterial infections by cold shock proteins and NF-kappaB signaling in healthy and immunosuppressed elderly patients

Supervisors

Prof. Dr. med. Peter Mertens (OVGU, MED, KNEP)

Prof. Dr. rer. nat. Ingo Schmitz (fomerly OVGU, MED, IMKI)

Publications

Shah A, Lindquist JA, Rosendahl L, Schmitz I, Mertens PR. (2021) Novel Insights into YB-1 Signaling and Cell Death Decisions. Cancers. 13(13):3306. doi:10.3390/cancers13133306.

Stojanovska V, Shah A, Woidacki K, Fischer F, Bauer M, Lindquist JA, Mertens PR, Zenclussen AC. (2021) YB-1 Is Altered in Pregnancy-Associated Disorders and Affects Trophoblast in Vitro Properties via Alternation of Multiple Molecular Traits. Int J Mol Sci. 22(13):7226.doi:10.3390/ijms22137226.

Shah A, Plaza-Sirvent C, Weinert S, Buchbinder JH, Lavrik IN, Mertens PR, Schmitz I, Lindquist JA. (2020) YB-1 Mediates TNF-Induced Pro-Survival Signaling by Regulating NF-κB Activation. Cancers, 12(8), 2188; DOI:10.3390/cancers12082188

Hessman CL, Hildebrandt J, Shah A, Brandt S, Bock A, Frye BC, Raffetseder U, Geffers R, Brunner-Weinzierl MC, Isermann B, Mertens PR, Lindquist JA. YB-1 Interferes with TNFα-TNFR Binding and Modulates Progranulin-Mediated Inhibition of TNFα Signaling. Int J Mol Sci. 2020 Sep 25;21(19):7076. DOI: 10.3390/ijms21197076.

Liakopoulos V, Jeron A, Shah A, Bruder D, Mertens PH, Gorny X (2018). Hemodialysis-related changes in phenotypical features of monocytes. Scientific Reports 8: 13694. DOI: 10.1038/s41598-018-31889-2